Biology

Differential Roles of MDA5 and RIG-I in the Recognition of RNA Viruses._KATO Hiroki and AKIRA Shizuo(Research Institute for Microbial Diseases)



The following is a comment on the published paper shown on the preceding page.

Differential Roles of MDA5 and RIG-I in the Recognition of RNA Viruses.
KATO Hiroki and AKIRA Shizuo (Research Institute for Microbial Diseases)

Introduction


Figure 1

MDA5 and RIG-I are involved in the detection of different types of dsRNA

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RIG-I and MDA5 detect different RNA viruses
Susceptibility of RIG-I -/- and MDA5 -/- mice against RNA viruses
Brief conclusion
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