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UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex_HANAOKA Fumio (Graduate School of Frontier Biosciences)

 



The following is a comment on the published paper shown on the preceding page.

UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex
HANAOKA Fumio (Graduate School of Frontier Biosciences)

Introduction

The XPC protein is ubiquitylated in response to UV irradiation


Figure 1

UV-DDB is required for the modification of XPC and physically interacts with XPC


Figure 2
   1 of 2 
The UV-DDB-E3 complex catalyzes the ubiquitylation of XPC in vitro
Ubiquitylation Alters the DNA-binding Properties of XPC and UV-DDB
Concluding remarks

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