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Seminars & Symposiums

GP2's Uptake of Intestinal Bacteria in the Intestinal Tract

2009-10-14 (Wed) 5:00 p.m. - 6:10 p.m.

52nd Graduate School of Frontier Biosciences Workshop

Hiroshi Ohno, team leader, Laboratory for Epithelial Immunobiology, Research Center for Allergy and Immunology, Riken

 

For a gut immunity system such as Peyer's patch to work, it is necessary to supply antigens into the gut lumen through the intestinal epithelia.

Special epithelial cells called M cells exist in the intestinal epithelia and they are thought to assume a role of transporting antigens from the intestinal epithelia to the intestinal immune system; however, details of differentiation and the functions of M cells have not been clarified.

As a result of examining specific genes in M cells, we found that a molecule called glycoprotein 2 (GP2) appears specifically in M cells and works as a receptor uptaking E. coli or salmonella and this is essential for an efficient immunological response.

Date: 2009-10-14 (Wed) 5:00 p.m. - 6:10 p.m.
Sponsored: COE Planning Office, Graduate School of Frontier Biosciences
Venue: Seminar Room, 3rd floor of Naobiology Builiding, Graduate School of Frontier Biosciences
Registration: Not required.
Contact: YOSHIMORI Tamotsu, Professor, Graduate School of Frontier Biosciences
tamyoshi@biken.osaka-u.ac.jp

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