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Research at OU

Biology

Phosphatidylserine-Dependent Engulfment by Macrophages of Nuclei from Erythroid Precursor Cells_YOSHIDA Hideyuki and NAGATA Shigekazu (Graduate School of Frontier Biosciences)

 



 

Semaphorin 7A Initiates T-cell-mediated Inflammatory Responses through α1β1 Integrin
SUZUKI Kazuhiro (Research Institute for Microbial Diseases)

Introduction

α1β1 integrin is the functional receptor for Sema7A


Figure 1

Sema7A stimulates macrophages at the immunological synapse


Figure 2

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Sema7A-/- mice are defective in T-cell-mediated immunity
Sema7A promotes regional inflammation
Conclusion

Research

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